16.5 Sex Hormones in Humans

2026 Syllabus Objectives

  1. Describe the roles of testosterone and oestrogen in the development and regulation of secondary sexual characteristics during puberty
  2. Describe the menstrual cycle in terms of changes in the ovaries and in the lining of the uterus
  3. Describe the sites of production of oestrogen and progesterone in the menstrual cycle and in pregnancy
  4. Explain the role of hormones in controlling the menstrual cycle and pregnancy, limited to FSH, LH, progesterone and oestrogen

Reproductive Hormones and Puberty 🔑

The functions of the reproductive organs are strongly influenced by hormones. The main reproductive hormones differ between males and females:

  • Males: Testosterone is the primary reproductive hormone
  • Females: Oestrogen and progesterone are the main reproductive hormones

Adolescence and Puberty

Adolescence is the period when a person approaches sexual maturity. During this time:

  • Sperm production begins in boys
  • Ovulation begins in girls

Puberty is the point at which sexual maturity is reached. This typically occurs a few years earlier in girls than in boys.

It's important to note that reaching puberty does not mean complete adulthood, as brain development and changes continue beyond this point.


Testosterone and Secondary Sexual Characteristics in Males 💪

Testosterone is secreted by the testes in males. During adolescence, the quantity of testosterone secreted greatly increases, triggering the development of secondary sexual characteristics.

Effects of Testosterone

The increased testosterone levels during puberty cause:

  • Growth of facial hair and pubic hair
  • Broadening of shoulders and general muscular development
  • Deepening of voice

Oestrogen and Secondary Sexual Characteristics in Females 👤

Oestrogen is secreted by the ovaries in females. This hormone is responsible for the development of female secondary sexual characteristics during puberty.

Effects of Oestrogen

Oestrogen causes:

  • Breast development and enlargement
  • Growth of pubic hair
  • Widening of hips

The Menstrual Cycle 📅

The menstrual cycle is a recurring sequence of events that prepares the female body for potential pregnancy. Understanding this cycle requires knowledge of changes in both the ovaries and the uterus lining.

Structure and Process

Follicles are small structures within the ovaries where eggs develop. After puberty, typically one egg is released from a follicle into the oviduct every month through a process called ovulation.

Changes in the Uterus Lining

Preparation Phase: Before the egg is released, the lining of the uterus becomes thick and spongy to prepare for a potential zygote. This lining is rich in tiny blood vessels that would supply the embryo with nutrients and oxygen if fertilization occurs.

Menstruation: If the egg is not fertilised, the spongy lining is not needed. It gradually breaks down and is lost through the vagina. This process is called menstruation or a period, and it typically lasts about five days.

Rebuilding Phase: After menstruation, the uterus lining builds up again to be ready to receive the next egg if it is fertilised.

The Menstrual Cycle Stages

The menstrual cycle can be divided into four main stages:

Stage 1 - Follicle Development: Inside the ovary, a follicle containing an egg cell develops. Simultaneously, the uterus lining is repaired after menstruation.

Stage 2 - Ovulation: The follicle bursts, releasing an egg cell from the ovary. This is when fertilisation could take place.

Stage 3 - Corpus Luteum Formation: The follicle transforms into a structure called the corpus luteum (also known as a yellow body). The uterus lining becomes more vascular and thicker, ready to receive an embryo.

Stage 4 - Menstruation (if no fertilisation): If the egg has not been fertilised, the thick uterus lining is not needed. It breaks down and is gradually lost through the vagina.

Sign in to view full notes